About: Tyrosine-Protein Kinase Receptor RET     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tyrosine-Protein Kinase Receptor RET
equivalentClass
OMIM_Number
  • 164761
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
Preferred_Name
  • Tyrosine-Protein Kinase Receptor RET
UMLS_CUI
  • C0919475
Legacy_Concept_Name
  • RET_Protein
FULL_SYN
  • Hydroxyaryl-Protein KinaseSYNCI
  • RETSYNCI
  • RET ProteinSYNCI
  • Glial Cell Line Derived Neurotrophic Factor Receptor ComponentSYNCI
  • Cadherin Family Member 12SYNCI
  • Tyrosine-Protein Kinase Receptor RETPTNCI
  • Proto-Oncogene c-RetSYNCI
  • EC 2.4.10.1SYNCI
Swiss_Prot
  • P07949
DEFINITION
  • Encoded by human RET Gene, Tyrosine-Protein Kinase Receptor RET is a type I membrane protein receptor for Glial Cell Line-Derived Neurotrophic Factor with an extracellular cadherin-like domain and important in neural crest development. Activation of the RET kinase results in autophosphorylation of tyrosine residues critical for signaling. RET mutations are associated with Hirschsprung's disease and Multiple Endocrine Neoplasia, pheochromocytoma, hyperparathyroidism and medullary thyroid cancer.NCI
code
  • C18539
is Has_Target of
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