About: Tumor Necrosis Factor Receptor Superfamily Member 10B     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tumor Necrosis Factor Receptor Superfamily Member 10B
equivalentClass
OMIM_Number
  • 603612
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
Preferred_Name
  • Tumor Necrosis Factor Receptor Superfamily Member 10B
UMLS_CUI
  • C0664123
ALT_DEFINITION
  • A protein on the surface of certain cells that binds another protein called TRAIL, which may kill some cancer cells. An increase in the amount or activity of death receptor 5 on cancer cells may kill more cells.NCI-GLOSS
Legacy_Concept_Name
  • TRAIL_Receptor-2
FULL_SYN
  • DR5PTNCI-GLOSSCDR0000641155
  • Tumor Necrosis Factor Receptor Superfamily Member 10BPTNCI
  • P53-Regulated DNA Damage-Inducible Cell Death Receptor (Killer)SYNCI
  • DR5SYNCI
  • Cytotoxic TRAIL Receptor-2SYNCI
  • Fas-Like Protein PrecursorSYNCI
  • Apoptosis Inducing Protein TRICK2A/2BSYNCI
  • TRAIL Receptor 2SYNCI
  • Death Receptor 5SYNCI
  • TRAIL-R2PTNCI-GLOSSCDR0000641153
  • TRAILR2SYNCI
  • tumor necrosis factor receptor superfamily member 10BPTNCI-GLOSSCDR0000641154
  • TRAIL-R2SYNCI
  • Tumor Necrosis Factor Receptor-Like Protein ZTNFR9SYNCI
  • TRAIL receptor 2PTNCI-GLOSSCDR0000641152
  • TNFRSF10BSYNCI
  • death receptor 5PTNCI-GLOSSCDR0000641151
Swiss_Prot
  • O14763
DEFINITION
  • Tumor necrosis factor receptor superfamily member 10B protein (440 aa, 48 kD) is a cell communication process protein that is encoded by the human TNFRSF10B gene and has a role in signal transduction.NCI
DesignNote
  • Receptor for Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL). In contrast to TRAILR1, TRAILR2 mediates apoptosis via the intracellular adaptor molecule FADD. Formation of a complex between TRAIL and receptors DR4 and DR5 triggers apoptosis by inducing the oligomerization of intracellular death domains.
code
  • C18178
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