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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Deuterated Phenanthrene
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Indicator, Reagent, or Diagnostic Aid
Preferred_Name
  • Deuterated Phenanthrene
NCI_META_CUI
  • CL437025
PDQ_Open_Trial_Search_ID
  • 736819
PDQ_Closed_Trial_Search_ID
  • 736819
FULL_SYN
  • Deuterated PhenanthrenePTNCI
  • Phenanthrene-D10SYNCI
  • [D10] phenanthreneSYNCI
  • [D10]PheABNCI
DEFINITION
  • A noncarcinogenic and structural analogue of polycyclic aromatic hydrocarbon (PAH), phenanthrene labeled with deuterium ([D10]Phe) with potential use in assessing an individual's capacity for PAH metabolism by the diol epoxide pathway. Upon oral or inhalation administration, [D10]Phe is metabolized into the tetraol end product ([D10]PheT) via the diol epoxide pathway, and can be quantified in urine. [D10]PheT can be used as a biomarker to assess PAHs metabolic activation and may therefore determine an individual's susceptibility to carcinogenicity upon PAH exposure.NCI
code
  • C102788
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