About: Peptide Nucleic Acid Clamping     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Peptide Nucleic Acid Clamping
rdfs:subClassOf
Semantic_Type
  • Laboratory Procedure
Preferred_Name
  • Peptide Nucleic Acid Clamping
NCI_META_CUI
  • CL433225
FULL_SYN
  • PCR ClampingSYNCI
  • PNA-clampingSYNCI
  • Peptide Nucleic Acid-mediated Competitive-PCR ClampingSYNCI
  • Peptide Nucleic Acid ClampSYNCI
  • Peptide Nucleic Acid ClampingPTNCI
  • PCR ClampSYNCI
DEFINITION
  • A modification of the standard polymerase chain reaction that increases the ability to preferentially amplify mutant alleles in the presence of an excess of wild-type molecules. Wild-type molecules are rendered inactive for amplification by binding of a peptide nucleic acid (PNA) probe that hybridizes to wild-type sequence with greater affinity and under less stringent conditions.NCI
code
  • C99487
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